Depends on how nice a lodge they want and what kind of fishing they want. I've stayed at some very nice places that are accessible to drive to, as well as being accessible to several different varieties of fishing, have also stayed at some places that were fine for me and my buddies, but probably wouldn't take my wife to . Let me know what kind of fish, ocean or river, and what kind of lodge and I can probably recommend something.
Stoney River Lodge, Curly Warren.
An awesome place, great food, great accommodations, waaaaay out in the wilderness 250 miles west of Anchorage, and great hunting and fishing.
Been there twice.
Fireweed Lodge in Klwock on Prince of Wales Island, just west of Ketchikan.
Been there once but will return, great accomodations, great (diverse) fishing opportunities.
wd